Locals Grill is a hamburger restaurant located in Florence, South Carolina, serving the 29505 area. Situated at 434 2nd Loop Road, this establishment specializes in offering a variety of hamburgers to its clientele. The restaurant operates with a commitment to accessibility, providing features such as wheelchair-accessible entrances, parking, restrooms, and seating to accommodate patrons with mobility needs.

The location is known for its convenient access and efforts to ensure an inclusive dining environment. Its presence in Florence contributes to the local dining options focused on casual hamburger fare. The restaurant maintains operations that prioritize both service and accessibility to meet the needs of a diverse customer base.

Locals Grill can be contacted via phone at 843-407-1199, allowing potential customers to inquire about menu options or other services. The business continues to serve the Florence community with a focus on providing straightforward hamburger offerings in an accessible setting.